Zoonotic Hantaviridae with Global Public Health Significance

Hantaviridae currently encompasses seven genera and 53 species. Multiple hantaviruses such as Hantaan virus, Seoul Dobrava-Belgrade Puumala Andes Sin Nombre virus are highly pathogenic to humans. They cause hemorrhagic fever with renal syndrome (HFRS) hantavirus cardiopulmonary or pulmonary (HCPS/HPS) in many countries. Some infect wild domestic animals without causing severe symptoms. Rodents, shrews, bats reservoirs of various mammalian hantaviruses. Recent years have witnessed significant advancements the study including genomics, taxonomy, evolution, replication, transmission, pathogenicity, control, patient treatment. Additionally, new infecting bats, rodents, amphibians, fish been identified. This review compiles these aid researchers public better recognizing this zoonotic family global health significance.